May 11-15, 2019, University of Genoa, Italy
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Welcome to the AIRR Community Meeting IV Video Portal. Below, you can find recordings of all our session talks.
Switch to our members-only section to download the slides!
Day 1
Workshop II: Jamie K Scott (Simon Fraser University, CA) — “Fundamentals of the Immune System” — No video available for this talk
Workshop II: Victor Greiff (University of Oslo, NO) — “Steps in AIRR data processing and Analysis: best practices, pitfalls and future directions” — No video available for this talk
Panel Discussion: Germline Databases (GLDB) WG — “Beyond inferred alleles: Improving the quality, scope and openness of GLDBs through software inference, open publication and population-level data” — Video
Day 2
Panel Discussion: Common Repositories, Data Representation and Minimal Standards WGs —
“Towards Solutions: The Benefits and Challenges of Sharing AIRR-seq Data” — Video
Day 3
Keynote: Sai Reddy (ETH Zurich, CH): “Integration of systems immunology and immune repertoires” — Video
Scientific Session I: Advances in Understanding Biological Processes of the AIRR
Talk 1: Nicholas Schwab (University of Muenster, DE): “Sex bias in MHC I-associated shaping of the adaptive immune system” — Video
Talk 2: Lindsay Cowell (University of Texas, Southwestern Medical Center, US): “Statistical classifiers for detecting phenotype-associated biophysicochemical motifs in AIRR” — Video
Talk 3: David Klatzmann (Sorbonne Universite, FR): “How specific is specific (in the T-cell response)?” — Video
Talk 4: Tom Parks (University of Oxford, UK): “Germline immunoglobulin heavy-chain locus variation and susceptibility to group A streptococcal disease” — Video
Poster Talks
Short Talk 1: Kenneth Hoehn (Yale University, US): ”Repertoire-wide phylogenetic models of B-cell molecular evolution reveal evolutionary signatures of aging and vaccination” — Video
Short Talk 2: Ivana Mikocziova (University of Oslo, NO): “AIRR-seq reveals a large number of germline polymorphisms in the variable immunoglobulin genes” — No video available for this talk
Short Talk 3: Pieter Meysman (University of Antwerp, BE): “On the viability of unsupervised T-cell receptor sequence clustering for epitope preference” — Video
Challenge Session I: Challenges in Processing and Storing Massive AIRR-seq Data (>1bn sequences)
Talk 1 – Processing & Annotation: Mikhail Shugay (Skolkovo Institute of Science and Technology, CZ): “Challenges in motif discovery and comparative analysis of large T-cell receptor repertoire datasets” — Video
Talk 2 – Analysis: Bryan Briney (Scripps Research, US): “Commonality despite exceptional diversity in the baseline human antibody repertoire” — Video
Talk 3 – Data Storage & Access: Xiao Liu (BGI Shenzhen, CN): “Pan Immunome Initiative and applications in health and disease” — Video
Day 4
Keynote: Antonio Lanzavecchia (Institute for Research in Biomedicine, CH): “Lessons from the analysis of the immune response to P. falciparum: The power of clonal selection” — No video available for this talk
Scientific Session II: Advances in AIRR-seq Data Addressing Human Health and Disease
Introduction: Steve Kleinstein (Yale School of Medicine, US) on sharing AIRR-seq data — Video
Talk 1: Rachael Bashford-Rogers (University of Oxford, UK): “Mapping B-cell receptor repertoires in immune-mediated diseases” — Video
Talk 2: Rob Holt (BC Cancer Research Centre, UBC/SFU, CA): “Mining the tumor-associated T cell repertoire for TCR therapeutics” — Video
Talk 3: Olga Britanova (Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, RU): “Potential use of monoclonal anti-TCR antibody for treatment of autoimmune diseases.” — Video
Talk 4: Ziv Shulman (The Weizmann Institute of Science, IL): “Dynamics of B cell immune responses in intestinal tissues” — Video
Poster Talks
Short Talk 1: Felix Breden (Simon Fraser University, CA): “iReceptor Plus facilitates sharing and analysis of AIRR-seq data” — Video
Short Talk 2: Xihao Hu (Dana Farber Cancer Institute, US): “Landscape of B-cell immunity and related immune evasion in human cancers” — Video
Short Talk 3: Keshav Motwani (University of Florida, US): “T-cell receptor repertoires in peripheral blood encode type-1 diabetes status” — Video
Patient and Community Engagement
Talk 1: Tania Bubela (Simon Fraser University, CA): “A primer on patient-oriented research” — Video
Talk 2: Harriet Teare (University of Oxford, UK): “Dynamic consent: Individual oversight and control of data and samples” — Video
Talk 3: Namaste Marsden (BC First Nations Health Authority, CA): “We are relational: The challenge of Indigenous collective rights in bio-ethics” — Video
Panel Discussion: Patient & Community Engagement — Video
Engaging Industry
Talk 1: Jacob Glanville (Distributed Bio, US): “Applied repertoire analysis – Computational immunoengineering of therapeutic antibodies and TCRs” — Video
Talk 2: Jonathan Carlson (Microsoft Research, US): “The Adaptive-Microsoft TCR-Antigen Map Project” — No video available for this talk
Talk 3: Nicola Bonzanni (Enpicom, NE): “Bridging the gap: Manage, analyze, visualize and interpret repertoire sequencing data using the IGX platform” — Video
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