Professor Charlotte Deane
Charlotte Deane is Professor of Structural Bioinformatics in the Department of Statistics at the University of Oxford and Chief Scientist of Biologics AI at Exscientia. She is also a co-director of the Systems Approaches to Biomedical Research Centre for Doctoral Training which she founded in 2009. She served on SAGE, the UK Government’s Scientific Advisory Group for Emergencies, during the COVID-19 pandemic, and acted as UK Research and Innovation’s COVID-19 Response Director. She has held numerous senior roles at the University of Oxford and until recently was the Deputy Executive Chair of the UK’s Engineering and Physical Sciences Research Council. At Oxford, Charlotte leads the Oxford Protein Informatics Group (OPIG), who work on diverse problems across immunoinformatics, protein structure and small molecule drug discovery; using statistics, AI and computation to generate biological and medical insight. Her work focuses on the development of novel algorithms, tools and databases that are openly available to the community. These tools are widely used web resources and are also part of several Pharma drug discovery pipelines. Charlotte is on several advisory boards and has consulted extensively with industry. She has set up a consulting arm within her own research group as a way of promoting industrial interaction and use of the group’s software tools.
Dr. Matthew Rayb
ould
Matthew Raybould is a postdoctoral researcher in the Oxford Protein Informatics Group, having completed his DPhil studies in the same group in 2020. His research to date has covered several areas in therapeutic antibody development and adaptive immune receptor repertoire analysis, combining deep-sequencing data with the latest 3D structure prediction techniques. Matt focusses on developing computational tools that aid the early stages of biologics drug discovery, often guided by improvements in our understanding of immune repertoires.
Dr. Fergus Boyles
Fergus Boyles is a research software engineer in the Oxford Protein Informatics Group (OPIG), where he is responsible for the development, maintenance, and deployment of OPIG’s databases and suite of antibody modelling tools. He is also a co-director of the EPSRC Sustainable Approaches to Biomedical Science: Responsible and Reproducible Research Centre for Doctoral Training. Previously, he completed his DPhil in OPIG, during which he focused on applying machine learning techniques to computer-aided drug discovery, an area of research he continues to pursue when not busy wrangling software.
