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We are excited to announce that AIRR Community Meeting V “Exploring New Frontiers” will be held in La Jolla, CA from December 8-12, 2020.
Meetings and presentations will take place at Scripps Research and the Hilton La Jolla Torrey Pines.
See AIRR C Meeting V Program at a Glance.
AIRR-C Executive Sub-committee member Christian Busse gave a talk at the deRSE2019 (Konferenz für ForschungssoftwareentwicklerInnen in Deutschland – Conference for software engineers in Germany) on building scientific communities using the AIRR-C as an example.
Check out his talk here: https://doi.org/10.5446/42486.
The fourth AIRR Community meeting (#AIRRC4) took place at the University of Genoa, May 11–15, 2019, in an unusual and gorgeous location. All talks were held in a 17th century church that has been repurposed for conference settings. The overarching theme of this meeting was “Bridging the Gaps” which aimed to address technological gaps between the amounts of accumulated data and our ability to process them, and the need for more involvement of stakeholder communities (industry, clinicians, patient communities) for the dissemination and implementation of the standards developed by the AIRR Community.
AIRR Community meetings are the premier event for research on adaptive immune-receptor repertoires. They are also the primary location where the AIRR-Community’s Working Groups and Sub-committees come together in one location to discuss how to push standardization in AIRR-sequencing (AIRR-seq) data and analysis forward. All meeting documents, slides, and video recordings can be found here:
https://www.antibodysociety.org/the-airr-community/meetings/communityiv/
Just like the biology of immune repertoires is high-dimensional, this meeting’s success was as well! We gathered some of the numbers that best describe the success of the AIRR C IV meeting.
Congratulations to The Antibody Society’s Adaptive Immune Repertoire Community on the publication of their newest paper, OGRDB: a reference database of inferred immune receptor genes, in Nucleic Acid Research. The paper is open access and can be freely downloaded here.
High-throughput sequencing of the adaptive immune receptor repertoire (AIRR-seq) is providing unprecedented insights into the immune response to disease and into the development of immune disorders. The accurate interpretation of AIRR-seq data depends on the existence of comprehensive germline gene reference sets. Current sets are known to be incomplete and unrepresentative of the degree of polymorphism and diversity in human and animal populations. A key issue is the complexity of the genomic regions in which they lie, which, because of the presence of multiple repeats, insertions and deletions, have not proved tractable with short-read whole genome sequencing. Recently, tools and methods for inferring such gene sequences from AIRR-seq datasets have become available, and a community approach has been developed for the expert review and publication of such inferences. Here, we present OGRDB, the Open Germline Receptor Database (https://ogrdb.airr-community.org), a public resource for the submission, review and publication of previously unknown receptor germline sequences together with supporting evidence.
On behalf of the AIRR-C Meetings Sub-committee we would like to thank the AIRR Community for their survey input on the theme for the next Meeting in December 2020. Further details with the date and location for AIRR Community Meeting V will be announced soon!
